Starting HRT in early menopause may reduce women’s risk of Alzheimer’s

Declines in oestrogen during menopause may have cognitive effects Elena Popova/Getty Images Beginning hormone replacement therapy (HRT) within five years of menopause onset appears to lower the risk of Alzheimer’s disease. Yet starting it later in life seems to have the opposite effect, suggesting the timing of HRT influences how it affects the brain. Women … Read more

You Can Now Inject Yourself With an Alzheimer’s Drug at Home

Self-testing and self-treating are becoming bigger trends in medicine, and now, you can conduct part of your treatment at home by yourself if you have Alzheimer’s disease. On Aug. 30, the U.S. Food and Drug Administration (FDA) approved the first at-home treatment for Alzheimer’s. Lecanemab, sold under the brand name Leqembi—which the FDA approved in … Read more

Low dose of lithium reverses Alzheimer’s symptoms in mice

An illustration of nerve cells affected by Alzheimer’s disease Science Photo Library / Alamy Stock Photo People with Alzheimer’s disease have lower levels of lithium in their brains, and giving lithium to mice with symptoms of the condition reverses cognitive decline. Together, the findings suggest that lithium deficiency could be a driver of Alzheimer’s disease … Read more

Dementia cases are rising faster in China than the rest of the world

Why are dementia cases soaring in China? Hanohikirf / Alamy Dementia rates are increasing more rapidly in China than almost anywhere else in the world, with cases more than quadrupling in the country over the past few decades. Daoying Geng at Fudan University in China and her colleagues analysed dementia rates in 204 countries and … Read more

‘G’ and his ‘lovely girl’: Gene Hackman penned poignant notes to wife amid Alzheimer’s battle

Authorities recently released a new cache of records in the death investigation of Gene Hackman and Betsy Arakawa — including a series of heartfelt notes the couple left for each other, revealing the close-knit nature of their relationship even as Hackman’s health declined amid a battle with Alzheimer’s. The letters are at times humorous, sad, … Read more

An Alzheimer’s Blood Test Might Predict Advanced Disease

With two new treatments for Alzheimer’s disease approved in recent years, there’s growing hope for people at risk of the memory-robbing condition. But tests to detect the condition still lag behind. Earlier diagnosis would mean that people could take advantage of the drugs sooner, when the medicines are most effective. Detection is currently tricky. Brain … Read more

We’re finally learning how perimenopause profoundly changes the brain

The first sign something was amiss was the tiredness. Then I started forgetting where I had left my phone or keys, only to find them in the fridge or kitchen cupboard. The breaking point came when I went to make a cup of tea before an important interview, only to return 45 minutes later to … Read more

‘Living in a reel’: How Alzheimer’s left Gene Hackman alone in his final days

Reuters Reporters gathered outside the gated community where Hackman and his wife died Actor Gene Hackman was alone. The two-time Academy Award winner didn’t make any calls and missed meals. Medical experts say it’s possible the 95-year-old, who was in declining health and suffering from advanced stages of Alzheimer’s disease, did not even realise his … Read more

We’ll learn about Ozempic’s potential for Alzheimer’s disease in 2025

The brain shrinkage observed in Alzheimer’s may be prevented by semaglutide, the drug in Ozempic ZEPHYR/Science Photo Library/Alamy Ozempic and Wegovy are already transforming how we treat type 2 diabetes and obesity, and from next year another condition affecting millions of people worldwide might be added to the list: Alzheimer’s disease. Two clinical trials investigating … Read more