oneoff

One-off gene-editing therapy could permanently lower cholesterol

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A light micrograph cross-section showing cholesterol-containing plaque in a heart artery NIGEL DOWNER/SCIENCE PHOTO LIBRARY The prospects for a one-time treatment that reduces the risk of heart disease for the rest of a person’s life just got brighter. In an initial trial, a single dose of a CRISPR gene-editing therapy lowered cholesterol levels without any … Read more

Peter Mullan’s return to the stage is a one-off: ‘I can’t afford it’

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Pauline McLean BBC Scotland Arts Correspondent Getty Images Peter Mullan has tended to avoid theatre due to the low wages When Peter Mullan steps on stage as legendary football manager Bill Shankly on Friday night, it will be for the first time in more than 30 years. Red or Dead is an adaptation of the … Read more